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Funded Projects

Identifying Risk Factors

Identifying Risk Factors

Approximately 30% of women who present with early breast cancer undergo mastectomy. The results of randomized clinical trials have shown that post mastectomy radiotherapy {PMRT} (radiation to the chest wall, nodes in the neck and nodes under the arm) reduces the risk...

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Novel Molecular Breast Imaging Camera

Novel Molecular Breast Imaging Camera

Imaging of the breast is an important tool in the early detection, diagnosis and monitoring of response to treatment in breast cancer. Mammography has been the gold standard for detection of breast cancer for many years. Mammographic findings are based on anatomic...

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Comprehensive Genomic Characteristics

Comprehensive Genomic Characteristics

Triple negative breast cancer (TNBC) refers to tumours where the estrogen receptor (ER) and progesterone receptor are negative. In addition, HER2 neu is not over-expressed. Hence the term, “triple negative”. TNBC can be associated with a poor prognosis. Clinically it...

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Hereditary Breast Cancer BRCA1/BRCA2

Hereditary Breast Cancer BRCA1/BRCA2

Hereditary breast cancer accounts for 5-10% of all breast cancer diagnoses and is primarily caused by changes (mutations) in two genes called BRCA1 and BRCA2. Female relatives found to carry a familial BRCA1/2 mutation are at high risk to develop breast and ovarian...

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Daily Partial Breast Irradiation

Daily Partial Breast Irradiation

BRIGHT provided funding to support a phase II randomized trial to evaluate the safety of two accelerated partial breast irradiation regimens, of different intensities, in women who had undergone lumpectomy for breast cancer. Sixty-two women were enrolled in Hamilton...

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