Bright Run funded projects

Much has been written about the potential to prevent cancer. Apart from stopping cigarette smoking and avoiding excess sun exposure, there is limited evidence to support other forms of cancer prevention. There have been some studies that suggest the potential for...

It has been recognized that an established tumor is able to shut down immune rejection cells so they cannot work. A glycoprotein called CD200 appears to be very important in this shut down process. CD200 suppresses NK cells, promotes the generation of regulatory T...

Doxorubicin is a chemotherapy drug used commonly in women who have undergone surgery for breast cancer to prevent recurrent cancer. Although it is a very effective agent in fighting breast cancer, it can cause permanent damage to the muscle of the heart. Approximately...

The study was completed. 71 eligible subjects with a median age of 52 (range: 40-87) were randomized to ALTENS (n=35) and control (n=36). At 12 weeks, there were 11 (31.4%) responders in the ALTENS arm versus 2 (5.5%) in the control (p=0.012). The results at 24 weeks...

Triple negative breast cancer (TNBC) refers to tumours where the estrogen receptor (ER) and progesterone receptor are negative. In addition, HER2 neu is not over-expressed. Hence the term, “triple negative”. TNBC can be associated with a poor prognosis. Clinically it...